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Last updated: 2016/11/27

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IL15 polyclonal antibody

  • Catalog # : PAB27236
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IL15.
  • Immunogen:
  • A synthetic peptide corresponding to 13 amino acids at internal region of human IL15.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least two isoforms of IL-15 are known to exist.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunohistochemistry (2.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of IL15 in rat spleen tissue with IL15 polyclonal antibody (Cat # PAB27236) at (lane 1) 1 and (lane 2) 2 ug/mL.
  • Immunohistochemistry
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3600
  • Gene Name:
  • IL15
  • Gene Alias:
  • IL-15,MGC9721
  • Gene Description:
  • interleukin 15
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000164617
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