TREM1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TREM1.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminus of human TREM1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for up to one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TREM1 in 293 cell lysate with TREM1 polyclonal antibody (Cat # PAB27220) at (lane 1) 1 and (lane 2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TREM1
Entrez GeneID
54210Protein Accession#
NP_061113Gene Name
TREM1
Gene Alias
TREM-1
Gene Description
triggering receptor expressed on myeloid cells 1
Omim ID
605085Gene Ontology
HyperlinkGene Summary
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM
Other Designations
OTTHUMP00000016370|triggering-receptor TREM1
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Interactome
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