CRB1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CRB1.
Immunogen
A synthetic peptide corresponding to 18 amino acids at internal region of human CRB1.
Host
Rabbit
Reactivity
Human
Specificity
Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of CRB1 in human small intestine tissue with CRB1 polyclonal antibody (Cat # PAB27209) at 1 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CRB1
Entrez GeneID
23418Protein Accession#
NP_001180569Gene Name
CRB1
Gene Alias
LCA8, RP12
Gene Description
crumbs homolog 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternatively spliced transcript variants have been observed but their full-length nature has yet to be determined. [provided by RefSeq
Other Designations
OTTHUMP00000033690|crumbs homolog 1
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Interactome
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Disease
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