PTPRD polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PTPRD in HeLa cell lysate with PTPRD polyclonal antibody (Cat # PAB27193) at (lane 1) 1 and (lane 2) 2 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PTPRD.
Immunogen
A synthetic peptide corresponding to 18 amino acids at N-terminus of human PTPRD.
Host
Rabbit
Reactivity
Human
Specificity
PTPRD antibody is human specific. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PTPRD in HeLa cell lysate with PTPRD polyclonal antibody (Cat # PAB27193) at (lane 1) 1 and (lane 2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PTPRD
Entrez GeneID
5789Protein Accession#
NP_569075Gene Name
PTPRD
Gene Alias
HPTP, HPTP-DELTA, HPTPD, MGC119750, MGC119751, MGC119752, MGC119753, PTPD, R-PTP-DELTA
Gene Description
protein tyrosine phosphatase, receptor type, D
Omim ID
601598Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000022727|protein tyrosine phosphatase delta|protein tyrosine phosphatase, receptor type, delta polypeptide
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Interactome
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Disease
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