MAP3K7IP3 polyclonal antibody
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More Files
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Immunohistochemistry
Immunohistochemistry analysis of MAP3K7IP3 in human kidney tissue with MAP3K7IP3 polyclonal antibody (Cat # PAB27183) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAP3K7IP3.
Immunogen
A synthetic peptide corresponding to 13 amino acids at N-terminus of human MAP3K7IP3.
Host
Rabbit
Reactivity
Human
Specificity
TAB3 antibody is human specific. TAB3 antibody is predicted not to cross-react with other TAB proteins.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry analysis of MAP3K7IP3 in human kidney tissue with MAP3K7IP3 polyclonal antibody (Cat # PAB27183) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MAP3K7IP3
Entrez GeneID
257397Protein Accession#
NP_690000Gene Name
MAP3K7IP3
Gene Alias
MGC45404, NAP1, TAB3
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 3
Omim ID
300480Gene Ontology
HyperlinkGene Summary
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3|NF-kappa-B-activating protein 1|NFkB activating protein 1|OTTHUMP00000023112|TAK1 binding protein 3|TAK1-binding protein 3
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