MAP3K7IP2 polyclonal antibody
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More Files
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Immunohistochemistry
Immunohistochemistry analysis of MAP3K7IP2 in human brain tissue with MAP3K7IP2 polyclonal antibody (Cat # PAB27182) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAP3K7IP2.
Immunogen
A synthetic peptide corresponding to 14 amino acids at C-terminus of human MAP3K7IP2.
Host
Rabbit
Reactivity
Human
Specificity
MAP3K7IP2 antibody is human specific. MAP3K7IP2 antibody is predicted not to cross-react with other TAB proteins.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry analysis of MAP3K7IP2 in human brain tissue with MAP3K7IP2 polyclonal antibody (Cat # PAB27182) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MAP3K7IP2
Entrez GeneID
23118Protein Accession#
NP_055908Gene Name
MAP3K7IP2
Gene Alias
FLJ21885, KIAA0733, TAB2
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Omim ID
605101Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations
OTTHUMP00000017388|OTTHUMP00000040125|TAK1-binding protein 2
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