PHOX2B polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PHOX2B.
Immunogen
A synthetic peptide corresponding to 15 amino acids at internal region of human PHOX2B.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
PHOX2B antibody is predicted to not cross-react with other paired homeobox family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PHOX2B in 293 cell lysate with PHOX2B polyclonal antibody (Cat # PAB27175) at (lane 1) 1 and (lane 2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PHOX2B
Entrez GeneID
8929Protein Accession#
NP_003915Gene Name
PHOX2B
Gene Alias
NBPhox, PMX2B
Gene Description
paired-like homeobox 2b
Gene Ontology
HyperlinkGene Summary
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq
Other Designations
PHOX2B homeodomain protein|neuroblastoma paired-type homeobox protein|paired mesoderm homeobox 2b
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Diseases
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