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Last updated: 2016/12/4
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AIRE polyclonal antibody

  • Catalog # : PAB27146
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AIRE.
  • Immunogen:
  • A synthetic peptide corresponding to human AIRE.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 60
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • AIRE polyclonal antibody detects endogenous levels of AIRE protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of 293 cell lysate with AIRE polyclonal antibody (Cat # PAB27146).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 326
  • Gene Name:
  • AIRE
  • Gene Alias:
  • AIRE1,APECED,APS1,APSI,PGA1
  • Gene Description:
  • autoimmune regulator
  • Gene Summary:
  • This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). [provided by RefSeq
  • Other Designations:
  • autoimmune polyendocrinopathy candidiasis ectodermal dystrophy
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