SNAI1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SNAI1.
Immunogen
A synthetic peptide corresponding to human SNAI1.
Host
Rabbit
Theoretical MW (kDa)
29
Reactivity
Human, Mouse
Specificity
SNAI1 polyclonal antibody detects endogenous levels of SNAI1 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HT-29 cell lysate with SNAI1 polyclonal antibody (Cat # PAB27142).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using SNAI1 polyclonal antibody (Cat # PAB27142).Immunofluorescence
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Gene Info — SNAI1
Entrez GeneID
6615Protein Accession#
O95863Gene Name
SNAI1
Gene Alias
SLUGH2, SNA, SNAH, dJ710H13.1
Gene Description
snail homolog 1 (Drosophila)
Omim ID
604238Gene Ontology
HyperlinkGene Summary
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq
Other Designations
OTTHUMP00000031680|snail 1 homolog|snail 1 zinc finger protein|snail 1, zinc finger protein
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Interactome
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Pathway
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Disease
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Publication Reference
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High glucose restrains acetylcholine-induced keratinocyte EMT is mitigated by p38 inhibition.
Mark Wei Yi Tan, Wei Ren Tan, Ze Qing Kong, Jun Hong Toh, Wei Kiat Jonathan Wee, Erica Mei Ling Teo, Hong Sheng Cheng, Xiaomeng Wang, Nguan Soon Tan.
The Journal of Investigative Dermatology 2021 Jun; 141(6):1438.
Application:IF, IHC, WB-Ce, Human, Human keratinocytes, Mouse epithelial tongue.
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High glucose restrains acetylcholine-induced keratinocyte EMT is mitigated by p38 inhibition.
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