FOSB polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with FOSB polyclonal antibody (Cat # PAB27124).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using FOSB polyclonal antibody (Cat # PAB27124).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FOSB.
Immunogen
A synthetic peptide corresponding to human FOSB.
Host
Rabbit
Theoretical MW (kDa)
35
Reactivity
Human, Mouse
Specificity
FOSB polyclonal antibody detects endogenous levels of FOSB protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with FOSB polyclonal antibody (Cat # PAB27124).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using FOSB polyclonal antibody (Cat # PAB27124).Immunofluorescence
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Gene Info — FOSB
Entrez GeneID
2354Protein Accession#
P53539Gene Name
FOSB
Gene Alias
AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291
Gene Description
FBJ murine osteosarcoma viral oncogene homolog B
Omim ID
164772Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
activator protein 1|oncogene FOS-B
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Interactome
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Disease
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