EPB49 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EPB49.
Immunogen
A synthetic peptide corresponding to human EPB49.
Host
Rabbit
Theoretical MW (kDa)
50
Reactivity
Human, Mouse
Specificity
EPB49 polyclonal antibody detects endogenous levels of EPB49 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with EPB49 polyclonal antibody (Cat # PAB27123).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human heart tissue using EPB49 polyclonal antibody (Cat # PAB27123).Immunofluorescence
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Gene Info — EPB49
Entrez GeneID
2039Protein Accession#
Q08495Gene Name
EPB49
Gene Alias
DMT, FLJ78462, FLJ98848
Gene Description
erythrocyte membrane protein band 4.9 (dematin)
Omim ID
125305Gene Ontology
HyperlinkGene Summary
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).[supplied by OMIM
Other Designations
dematin|erythrocyte membrane protein band 4.9
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