XRCC6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of XRCC6.
Immunogen
A synthetic peptide corresponding to human XRCC6.
Host
Rabbit
Theoretical MW (kDa)
~70.0
Reactivity
Human, Mouse
Specificity
XRCC6 polyclonal antibody detects endogenous levels of XRCC6 protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with XRCC6 polyclonal antibody (Cat # PAB27105) at 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using XRCC6 polyclonal antibody (Cat # PAB27105). -
Gene Info — XRCC6
Entrez GeneID
2547Protein Accession#
P12956Gene Name
XRCC6
Gene Alias
CTC75, CTCBF, G22P1, KU70, ML8, TLAA
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 6
Omim ID
152690Gene Ontology
HyperlinkGene Summary
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq
Other Designations
ATP-dependent DNA helicase II, 70 kDa subunit|CTC box binding factor 75 kDa subunit|Ku autoantigen p70 subunit|Ku autoantigen, 70kDa|OTTHUMP00000028581|thyroid autoantigen 70kD (Ku antigen)|thyroid autoantigen 70kDa (Ku antigen)|thyroid-lupus autoantigen
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Interactome
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