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UBR5 polyclonal antibody

  • Catalog # : PAB27095
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of UBR5.
  • Immunogen:
  • A synthetic peptide corresponding to human UBR5.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 309
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • UBR5 polyclonal antibody detects endogenous levels of UBR5 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of A-549 cell lysate with UBR5 polyclonal antibody (Cat # PAB27095).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using UBR5 polyclonal antibody (Cat # PAB27095).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • UBR5
  • Gene Alias:
  • DD5,EDD,EDD1,FLJ11310,HYD,KIAA0896,MGC57263
  • Gene Description:
  • ubiquitin protein ligase E3 component n-recognin 5
  • Gene Summary:
  • This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq
  • Other Designations:
  • E3 identified by differential display,E3 ubiquitin protein ligase, HECT domain containing, 1,hyperplastic discs protein homolog,progestin induced protein,ubiquitin-protein ligase
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