UBR5 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of A-549 cell lysate with UBR5 polyclonal antibody (Cat # PAB27095).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using UBR5 polyclonal antibody (Cat # PAB27095).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of UBR5.
Immunogen
A synthetic peptide corresponding to human UBR5.
Host
Rabbit
Theoretical MW (kDa)
309
Reactivity
Human, Mouse
Specificity
UBR5 polyclonal antibody detects endogenous levels of UBR5 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of A-549 cell lysate with UBR5 polyclonal antibody (Cat # PAB27095).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using UBR5 polyclonal antibody (Cat # PAB27095). -
Gene Info — UBR5
Entrez GeneID
51366Protein Accession#
O95071Gene Name
UBR5
Gene Alias
DD5, EDD, EDD1, FLJ11310, HYD, KIAA0896, MGC57263
Gene Description
ubiquitin protein ligase E3 component n-recognin 5
Omim ID
608413Gene Ontology
HyperlinkGene Summary
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq
Other Designations
E3 identified by differential display|E3 ubiquitin protein ligase, HECT domain containing, 1|hyperplastic discs protein homolog|progestin induced protein|ubiquitin-protein ligase
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Interactome
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Pathway
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