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HDAC5/HDAC9 polyclonal antibody

  • Catalog # : PAB27090
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HDAC5/HDAC9.
  • Immunogen:
  • A synthetic peptide corresponding to human HDAC5/HDAC9.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 121
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • HDAC5/HDAC9 polyclonal antibody detects endogenous levels of HDAC5/HDAC9 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HepG2 cell lysate with HDAC5/HDAC9 polyclonal antibody (Cat # PAB27090).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using HDAC5/HDAC9 polyclonal antibody (Cat # PAB27090).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Protein Accession#:
  • Q9UQL6 (Gene ID : 10014);Q9UKV0 (Gene ID : 9734)
  • Gene Name:
  • HDAC5
  • Gene Alias:
  • FLJ90614,HD5,NY-CO-9
  • Gene Description:
  • histone deacetylase 5
  • Gene Summary:
  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen NY-CO-9
  • Gene Information
  • Entrez GeneID:
  • 9734
  • Protein Accession#:
  • Q9UQL6 (Gene ID : 10014);Q9UKV0 (Gene ID : 9734)
  • Gene Name:
  • HDAC9
  • Gene Alias:
  • DKFZp779K1053,HD7,HDAC,HDAC7,HDAC7B,HDAC9B,HDAC9FL,HDRP,KIAA0744,MITR
  • Gene Description:
  • histone deacetylase 9
  • Gene Summary:
  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq
  • Other Designations:
  • MEF-2 interacting transcription repressor (MITR) protein,histone deacetylase 4/5-related protein,histone deacetylase 7,histone deacetylase 7B
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