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CDKN2C polyclonal antibody

  • Catalog # : PAB27081
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CDKN2C.
  • Immunogen:
  • A synthetic peptide corresponding to human CDKN2C.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 15
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • CDKN2C polyclonal antibody detects endogenous levels of CDKN2C protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysate with CDKN2C polyclonal antibody (Cat # PAB27081) at 1:500 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using CDKN2C polyclonal antibody (Cat # PAB27081).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1031
  • Gene Name:
  • CDKN2C
  • Gene Alias:
  • INK4C,p18,p18-INK4C
  • Gene Description:
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • Gene Summary:
  • The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq
  • Other Designations:
  • CDK6 inhibitor p18,OTTHUMP00000009730,OTTHUMP00000009731,OTTHUMP00000046546,cyclin-dependent inhibitor,cyclin-dependent kinase 4 inhibitor C,cyclin-dependent kinase 6 inhibitor p18,cyclin-dependent kinase inhibitor 2C
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