CDKN2C polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with CDKN2C polyclonal antibody (Cat # PAB27081) at 1:500 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using CDKN2C polyclonal antibody (Cat # PAB27081).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDKN2C.
Immunogen
A synthetic peptide corresponding to human CDKN2C.
Host
Rabbit
Theoretical MW (kDa)
15
Reactivity
Human, Mouse
Specificity
CDKN2C polyclonal antibody detects endogenous levels of CDKN2C protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with CDKN2C polyclonal antibody (Cat # PAB27081) at 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using CDKN2C polyclonal antibody (Cat # PAB27081). -
Gene Info — CDKN2C
Entrez GeneID
1031Protein Accession#
P42773Gene Name
CDKN2C
Gene Alias
INK4C, p18, p18-INK4C
Gene Description
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Omim ID
603369Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq
Other Designations
CDK6 inhibitor p18|OTTHUMP00000009730|OTTHUMP00000009731|OTTHUMP00000046546|cyclin-dependent inhibitor|cyclin-dependent kinase 4 inhibitor C|cyclin-dependent kinase 6 inhibitor p18|cyclin-dependent kinase inhibitor 2C
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Interactome
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Pathway
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Disease
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