MCM3AP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MCM3AP.
Immunogen
A synthetic peptide corresponding to human MCM3AP.
Host
Rabbit
Theoretical MW (kDa)
218
Reactivity
Human, Mouse
Specificity
MCM3AP polyclonal antibody detects endogenous levels of MCM3AP protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NIH/3T3 cell lysate with MCM3AP polyclonal antibody (Cat # PAB27068).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using MCM3AP polyclonal antibody (Cat # PAB27068). -
Gene Info — MCM3AP
Entrez GeneID
8888Protein Accession#
O60318Gene Name
MCM3AP
Gene Alias
FLJ44336, FLJ45306, GANP, KIAA0572, MAP80
Gene Description
minichromosome maintenance complex component 3 associated protein
Omim ID
603294Gene Ontology
HyperlinkGene Summary
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. [provided by RefSeq
Other Designations
MCM3 import protein|MCM3 minichromosome maintenance deficient 3 associated protein|OTTHUMP00000115776|germinal center-associated nuclear protein|minichromosome maintenance deficient 3-associated protein
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