EEF2K polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of EEF2K polyclonal antibody (Cat # PAB27059) in extracts from HeLa cells at 1:500 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of EEF2K polyclonal antibody (Cat # PAB27059) in paraffin-embedded human breast carcinoma tissue.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EEF2K.
Immunogen
A synthetic peptide corresponding to human EEF2K.
Host
Rabbit
Theoretical MW (kDa)
~88
Reactivity
Human, Rat
Specificity
EEF2K polyclonal antibody detects endogenous levels of EEF2K protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of EEF2K polyclonal antibody (Cat # PAB27059) in extracts from HeLa cells at 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of EEF2K polyclonal antibody (Cat # PAB27059) in paraffin-embedded human breast carcinoma tissue.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EEF2K
Entrez GeneID
29904Protein Accession#
O00418Gene Name
EEF2K
Gene Alias
HSU93850, MGC45041, eEF-2K
Gene Description
eukaryotic elongation factor-2 kinase
Omim ID
606968Gene Ontology
HyperlinkGene Summary
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq
Other Designations
calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase|calmodulin-dependent protein kinase III|eEF-2 kinase|elongation factor-2 kinase
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Interactome
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Disease
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