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Last updated: 2016/10/23
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IL4R polyclonal antibody

  • Catalog # : PAB26977
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IL4R.
  • Immunogen:
  • A synthetic peptide corresponding to human IL4R.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • ~88.0
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • IL4R polyclonal antibody detects endogenous levels of IL4R protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of A-549 cell lysate with IL4R polyclonal antibody (Cat # PAB26977) at 1:500 dilution.
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 3566
  • Gene Name:
  • IL4R
  • Gene Alias:
  • CD124,IL4RA
  • Gene Description:
  • interleukin 4 receptor
  • Gene Summary:
  • This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000122506,interleukin 4 receptor alpha chain,interleukin-4 receptor alpha chain
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