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Last updated: 2017/4/23
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ZIC1/ZIC2/ZIC3 polyclonal antibody

  • Catalog # : PAB26961
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ZIC1/ZIC2/ZIC3.
  • Immunogen:
  • A synthetic peptide corresponding to human ZIC1/ZIC2/ZIC3.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 51
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • ZIC1/ZIC2/ZIC3 polyclonal antibody detects endogenous levels of ZIC1/ZIC2/ZIC3 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Jurkat cell lysate with ZIC1/ZIC2/ZIC3 polyclonal antibody (Cat # PAB26961).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human brain tissue using ZIC1/ZIC2/ZIC3 polyclonal antibody (Cat # PAB26961).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 7545
  • Protein Accession#:
  • Q15915(Gene ID : 7545);O95409(Gene ID : 7546);O60481(Gene ID : 7547)
  • Gene Name:
  • ZIC1
  • Gene Alias:
  • ZIC,ZNF201
  • Gene Description:
  • Zic family member 1 (odd-paired homolog, Drosophila)
  • Gene Summary:
  • This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq
  • Other Designations:
  • Zic family member 1 (odd-paired Drosophila homolog),Zinc finger protein of the cerebellum 1,zinc finger protein of the cerebellum 1
  • Gene Information
  • Entrez GeneID:
  • 7546
  • Protein Accession#:
  • Q15915(Gene ID : 7545);O95409(Gene ID : 7546);O60481(Gene ID : 7547)
  • Gene Name:
  • ZIC2
  • Gene Alias:
  • HPE5
  • Gene Description:
  • Zic family member 2 (odd-paired homolog, Drosophila)
  • Gene Summary:
  • This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018633,Zic family member 2 (odd-paired Drosophila homolog),Zinc finger protein of the cerebellum 2,zinc finger protein of the cerebellum 2
  • Gene Information
  • Entrez GeneID:
  • 7547
  • Protein Accession#:
  • Q15915(Gene ID : 7545);O95409(Gene ID : 7546);O60481(Gene ID : 7547)
  • Gene Name:
  • ZIC3
  • Gene Alias:
  • HTX,HTX1,ZNF203
  • Gene Description:
  • Zic family member 3 (odd-paired homolog, Drosophila)
  • Gene Summary:
  • This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024142,heterotaxy 1,zinc finger protein of the cerebellum 3
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