FZD7 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HT-29 cell lysate with FZD7 polyclonal antibody (Cat # PAB26951).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FZD7.
Immunogen
A synthetic peptide corresponding to human FZD7.
Host
Rabbit
Theoretical MW (kDa)
64
Reactivity
Human, Mouse
Specificity
FZD7 polyclonal antibody detects endogenous levels of FZD7 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HT-29 cell lysate with FZD7 polyclonal antibody (Cat # PAB26951).Immunofluorescence
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Gene Info — FZD7
Entrez GeneID
8324Protein Accession#
O75084Gene Name
FZD7
Gene Alias
FzE3
Gene Description
frizzled homolog 7 (Drosophila)
Omim ID
603410Gene Ontology
HyperlinkGene Summary
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq
Other Designations
Frizzled, drosophila, homolog of, 7|frizzled 7
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Interactome
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Pathway
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Disease
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