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IL7R polyclonal antibody

  • Catalog # : PAB26934
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IL7R.
  • Immunogen:
  • A synthetic peptide corresponding to human IL7R.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 52
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • IL7R polyclonal antibody detects endogenous levels of IL7R protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of K-562 cell lysate treated with insulin 0.01 U. Using IL7R polyclonal antibody (Cat # PAB26934).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3575
  • Gene Name:
  • IL7R
  • Gene Alias:
  • CD127,CDW127,IL-7R-alpha,IL7RA,ILRA
  • Gene Description:
  • interleukin 7 receptor
  • Gene Summary:
  • The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq
  • Other Designations:
  • CD127 antigen,interleukin 7 receptor alpha chain
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