FES polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate treated with serum 20%, 30'. Using FES polyclonal antibody (Cat # PAB26915).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver carcinoma tissue using FES polyclonal antibody (Cat # PAB26915).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FES.
Immunogen
A synthetic peptide corresponding to human FES.
Host
Rabbit
Theoretical MW (kDa)
80
Reactivity
Human, Mouse
Specificity
FES polyclonal antibody detects endogenous levels of FES protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate treated with serum 20%, 30'. Using FES polyclonal antibody (Cat # PAB26915).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver carcinoma tissue using FES polyclonal antibody (Cat # PAB26915). -
Gene Info — FES
Entrez GeneID
2242Protein Accession#
P07332Gene Name
FES
Gene Alias
FPS
Gene Description
feline sarcoma oncogene
Omim ID
190030Gene Ontology
HyperlinkGene Summary
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms
Other Designations
Oncogene FES, feline sarcoma virus|c-fes/fps protein|feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog|proto-oncogene tyrosine-protein kinase Fes/Fps
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Interactome
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Pathway
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Disease
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