MED17 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HT-29 cell lysate with MED17 polyclonal antibody (Cat # PAB26898).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using MED17 polyclonal antibody (Cat # PAB26898).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MED17.
Immunogen
A synthetic peptide corresponding to human MED17.
Host
Rabbit
Theoretical MW (kDa)
73
Reactivity
Human, Mouse
Specificity
MED17 polyclonal antibody detects endogenous levels of MED17 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HT-29 cell lysate with MED17 polyclonal antibody (Cat # PAB26898).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using MED17 polyclonal antibody (Cat # PAB26898). -
Gene Info — MED17
Entrez GeneID
9440Protein Accession#
Q9NVC6Gene Name
MED17
Gene Alias
CRSP6, CRSP77, DRIP80, FLJ10812, TRAP80
Gene Description
mediator complex subunit 17
Omim ID
603810Gene Ontology
HyperlinkGene Summary
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq
Other Designations
cofactor required for Sp1 transcriptional activation, subunit 6 (77kD)|cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa|thyroid hormone receptor-associated protein, 80-KD subunit|vitamin D receptor interacting protein 80-kD
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Interactome
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