MKL1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with MKL1 polyclonal antibody (Cat # PAB26897).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MKL1.
Immunogen
A synthetic peptide corresponding to human MKL1.
Host
Rabbit
Theoretical MW (kDa)
99
Reactivity
Human, Mouse
Specificity
MKL1 polyclonal antibody detects endogenous levels of MKL1 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with MKL1 polyclonal antibody (Cat # PAB26897).Immunohistochemistry
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Gene Info — MKL1
Entrez GeneID
57591Protein Accession#
Q969V6Gene Name
MKL1
Gene Alias
BSAC, MAL, MRTF-A
Gene Description
megakaryoblastic leukemia (translocation) 1
Omim ID
606078Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq
Other Designations
OTTHUMP00000028831|RBM15/MKL1 fusion|RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein|basic, SAP and coiled-coil domain|megakaryoblastic leukemia 1|megakaryoblastic leukemia 1 protein|megakaryocytic acute leukemia|myocardin-related
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Interactome
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Disease
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