TMPRSS3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TMPRSS3.
Immunogen
A synthetic peptide corresponding to human TMPRSS3.
Host
Rabbit
Theoretical MW (kDa)
49
Reactivity
Human, Mouse
Specificity
TMPRSS3 polyclonal antibody detects endogenous levels of TMPRSS3 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with TMPRSS3 polyclonal antibody (Cat # PAB26891).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using TMPRSS3 polyclonal antibody (Cat # PAB26891).Immunofluorescence
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Gene Info — TMPRSS3
Entrez GeneID
64699Protein Accession#
P57727Gene Name
TMPRSS3
Gene Alias
DFNB10, DFNB8, ECHOS1, TADG12
Gene Description
transmembrane protease, serine 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
OTTHUMP00000109345|serine protease TADG12
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Interactome
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Disease
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