MAP4K4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with MAP4K4 polyclonal antibody (Cat # PAB26885).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAP4K4.
Immunogen
A synthetic peptide corresponding to human MAP4K4.
Host
Rabbit
Theoretical MW (kDa)
142
Reactivity
Human, Mouse
Specificity
MAP4K4 polyclonal antibody detects endogenous levels of MAP4K4 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with MAP4K4 polyclonal antibody (Cat # PAB26885).Immunofluorescence
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Gene Info — MAP4K4
Entrez GeneID
9448Protein Accession#
O95819Gene Name
MAP4K4
Gene Alias
FLH21957, FLJ10410, FLJ20373, FLJ90111, HGK, KIAA0687, NIK
Gene Description
mitogen-activated protein kinase kinase kinase kinase 4
Omim ID
604666Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
HPK/GCK-like kinase|hepatocyte progenitor kinase-like/germinal center kinase-like kinase
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Interactome
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