E2F2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with E2F2 polyclonal antibody (Cat # PAB26868).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using E2F2 polyclonal antibody (Cat # PAB26868).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of E2F2.
Immunogen
A synthetic peptide corresponding to human E2F2.
Host
Rabbit
Theoretical MW (kDa)
48
Reactivity
Human, Mouse
Specificity
E2F2 polyclonal antibody detects endogenous levels of E2F2 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with E2F2 polyclonal antibody (Cat # PAB26868).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using E2F2 polyclonal antibody (Cat # PAB26868). -
Gene Info — E2F2
Entrez GeneID
1870Protein Accession#
Q14209Gene Name
E2F2
Gene Alias
E2F-2
Gene Description
E2F transcription factor 2
Omim ID
600426Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq
Other Designations
OTTHUMP00000003257
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Interactome
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