LTB polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LTB.
Immunogen
A synthetic peptide corresponding to human LTB.
Host
Rabbit
Theoretical MW (kDa)
22
Reactivity
Human, Mouse
Specificity
LTB polyclonal antibody detects endogenous levels of LTB protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with LTB polyclonal antibody (Cat # PAB26866).Immunofluorescence
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Gene Info — LTB
Entrez GeneID
4050Protein Accession#
Q06643Gene Name
LTB
Gene Alias
TNFC, TNFSF3, p33
Gene Description
lymphotoxin beta (TNF superfamily, member 3)
Omim ID
600978Gene Ontology
HyperlinkGene Summary
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000029185|OTTHUMP00000038214|lymphotoxin-beta|tumor necrosis factor C
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