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STAT2 polyclonal antibody

  • Catalog # : PAB26848
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of STAT2.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y690 of human STAT2.
  • Sequence:
  • R-K-Yp-L-K
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 113
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity chromatography
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from HeLa cell and HL-60 cell using STAT2 polyclonal antibody (Cat # PAB26848).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using STAT2 polyclonal antibody (Cat # PAB26848).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6773
  • Gene Name:
  • STAT2
  • Gene Alias:
  • ISGF-3,MGC59816,P113,STAT113
  • Gene Description:
  • signal transducer and activator of transcription 2, 113kDa
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq
  • Other Designations:
  • interferon alpha induced transcriptional activator,signal transducer and activator of transcription 2
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