STAT2 polyclonal antibody

Catalog # PAB26848

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Size:100 ug
Price: USD $ 329.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of extracts from HeLa cell and HL-60 cell using STAT2 polyclonal antibody (Cat # PAB26848).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using STAT2 polyclonal antibody (Cat # PAB26848).

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of STAT2.

    Immunogen

    A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y690 of human STAT2.

    Sequence

    R-K-Yp-L-K

    Host

    Rabbit

    Theoretical MW (kDa)

    113

    Reactivity

    Human

    Form

    Liquid

    Purification

    Affinity chromatography

    Concentration

    1 mg/mL

    Recommend Usage

    Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of extracts from HeLa cell and HL-60 cell using STAT2 polyclonal antibody (Cat # PAB26848).

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using STAT2 polyclonal antibody (Cat # PAB26848).
  • Gene Info — STAT2

    Entrez GeneID

    6773

    Protein Accession#

    P52630

    Gene Name

    STAT2

    Gene Alias

    ISGF-3, MGC59816, P113, STAT113

    Gene Description

    signal transducer and activator of transcription 2, 113kDa

    Omim ID

    600556

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq

    Other Designations

    interferon alpha induced transcriptional activator|signal transducer and activator of transcription 2

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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