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PIK3R1/PIK3R2/PIK3R3 polyclonal antibody

  • Catalog # : PAB26835
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PIK3R1/PIK3R2/PIK3R3.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y467/Y199/Y464 of human PIK3R1/PIK3R2/PIK3R3.
  • Sequence:
  • L-Yp- E-E-Y
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 85
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity chromatography
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PIK3R1/PIK3R2/PIK3R3 polyclonal antibody (Cat # PAB26835).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5295
  • Protein Accession#:
  • P27986 (Gene ID : 5295);O00459 (Gene ID : 5296);Q92569 (Gene ID : 8503)
  • Gene Name:
  • PIK3R1
  • Gene Alias:
  • GRB1,p85,p85-ALPHA
  • Gene Description:
  • phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • Gene Summary:
  • Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha),phosphatidylinositol 3-kinase, regulatory, 1,phosphatidylinositol 3-kinase-associated p-85 alpha,phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha),phosphoinositide-3-ki
  • Gene Information
  • Entrez GeneID:
  • 5296
  • Protein Accession#:
  • P27986 (Gene ID : 5295);O00459 (Gene ID : 5296);Q92569 (Gene ID : 8503)
  • Gene Name:
  • PIK3R2
  • Gene Alias:
  • P85B,p85,p85-BETA
  • Gene Description:
  • phosphoinositide-3-kinase, regulatory subunit 2 (beta)
  • Other Designations:
  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta),phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta),phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
  • Gene Information
  • Entrez GeneID:
  • 8503
  • Protein Accession#:
  • P27986 (Gene ID : 5295);O00459 (Gene ID : 5296);Q92569 (Gene ID : 8503)
  • Gene Name:
  • PIK3R3
  • Gene Alias:
  • DKFZp686P05226,FLJ41892,p55,p55-GAMMA
  • Gene Description:
  • phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
  • Other Designations:
  • 100% homology to SWISS-PROT Q92569,OTTHUMP00000009783,OTTHUMP00000009786,phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma),phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma),phosphoinositide-3-kinase, regulatory subun
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