PIK3R1/PIK3R2/PIK3R3 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PIK3R1/PIK3R2/PIK3R3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y467/Y199/Y464 of human PIK3R1/PIK3R2/PIK3R3.
Sequence
L-Yp- E-E-Y
Host
Rabbit
Theoretical MW (kDa)
85
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PIK3R1/PIK3R2/PIK3R3 polyclonal antibody (Cat # PAB26835). -
Gene Info — PIK3R1
Entrez GeneID
5295Protein Accession#
P27986 (Gene ID : 5295);O00459 (Gene ID : 5296);Q92569 (Gene ID : 8503)Gene Name
PIK3R1
Gene Alias
GRB1, p85, p85-ALPHA
Gene Description
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Omim ID
171833Gene Ontology
HyperlinkGene Summary
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)|phosphoinositide-3-ki
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Gene Info — PIK3R2
Entrez GeneID
5296Protein Accession#
P27986 (Gene ID : 5295);O00459 (Gene ID : 5296);Q92569 (Gene ID : 8503)Gene Name
PIK3R2
Gene Alias
P85B, p85, p85-BETA
Gene Description
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Omim ID
603157Gene Ontology
HyperlinkGene Summary
O
Other Designations
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)|phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
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Gene Info — PIK3R3
Entrez GeneID
8503Protein Accession#
P27986 (Gene ID : 5295);O00459 (Gene ID : 5296);Q92569 (Gene ID : 8503)Gene Name
PIK3R3
Gene Alias
DKFZp686P05226, FLJ41892, p55, p55-GAMMA
Gene Description
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Omim ID
606076Gene Ontology
HyperlinkGene Summary
O
Other Designations
100% homology to SWISS-PROT Q92569|OTTHUMP00000009783|OTTHUMP00000009786|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subun
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Interactome
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Pathway
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Disease
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