MTOR polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells using MTOR polyclonal antibody (Cat # PAB26759).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Imunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using MTOR polyclonal antibody (Cat # PAB26759).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MTOR.
Immunogen
A synthetic peptide corresponding to residues surrounding S2448 of human MTOR.
Sequence
T-D-Sp-Y-S
Host
Rabbit
Theoretical MW (kDa)
289
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells using MTOR polyclonal antibody (Cat # PAB26759).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Imunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using MTOR polyclonal antibody (Cat # PAB26759). -
Gene Info — MTOR
Entrez GeneID
2475Protein Accession#
P42345Gene Name
MTOR
Gene Alias
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gene Description
mechanistic target of rapamycin
Omim ID
601231Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
Other Designations
FK506 binding protein 12-rapamycin associated protein 1|FK506 binding protein 12-rapamycin associated protein 2|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1
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Interactome
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Pathway
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Disease
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