PGR polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from SK-OV-3 cells using PGR polyclonal antibody (Cat # PAB26656).
Immunofluorescence
Immunofluorescence staining of methanol-fixed HeLa cells using PGR polyclonal antibody (Cat # PAB26656, red).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PGR.
Immunogen
A synthetic peptide corresponding to residues surrounding S190 of human PGR.
Sequence
G-L-Sp-P-A
Host
Rabbit
Theoretical MW (kDa)
99
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from SK-OV-3 cells using PGR polyclonal antibody (Cat # PAB26656).Immunofluorescence
Immunofluorescence staining of methanol-fixed HeLa cells using PGR polyclonal antibody (Cat # PAB26656, red). -
Gene Info — PGR
Entrez GeneID
5241Protein Accession#
P06401Gene Name
PGR
Gene Alias
NR3C3, PR
Gene Description
progesterone receptor
Omim ID
607311Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
Other Designations
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Interactome
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Disease
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