MC3R polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human brain, cortex with MC3R polyclonal antibody (Cat # PAB26591). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MC3R.
Immunogen
A synthetic peptide corresponding to 18 amino acids from C-Terminus of human MC3R.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MC5R (78%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-12 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human brain, cortex with MC3R polyclonal antibody (Cat # PAB26591). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — MC3R
Entrez GeneID
4159Protein Accession#
P41968Gene Name
MC3R
Gene Alias
BMIQ9, MC3, MC3-R
Gene Description
melanocortin 3 receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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