BRDT polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of MDA-MB-435 cell lysate (35 ug/lane) with BRDT polyclonal antibody (Cat # PAB2658).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BRDT.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BRDT.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MDA-MB-435 cell lysate (35 ug/lane) with BRDT polyclonal antibody (Cat # PAB2658). -
Gene Info — BRDT
Entrez GeneID
676Protein Accession#
NP_997072;O14789Gene Name
BRDT
Gene Alias
BRD6
Gene Description
bromodomain, testis-specific
Omim ID
602144Gene Ontology
HyperlinkGene Summary
BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011809|testis-specific bromodomain protein
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Interactome
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Disease
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Publication Reference
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Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein.
Pivot-Pajot C, Caron C, Govin J, Vion A, Rousseaux S, Khochbin S.
Molecular and Cellular Biology 2003 Aug; 23(15):5354.
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Structure and ligand of a histone acetyltransferase bromodomain.
Dhalluin C, Carlson JE, Zeng L, He C, Aggarwal AK, Zhou MM.
Nature 1999 Jun; 399(6735):491.
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Identification and characterization of BRDT: A testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh.
Jones MH, Numata M, Shimane M.
Genomics 1997 Nov; 45(3):529.
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Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein.
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