Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human brain with MCHR1 polyclonal antibody (Cat # PAB26452). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq
G protein-coupled receptor 24,G-protein coupled receptor 24