Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human brain with MTNR1B polyclonal antibody (Cat # PAB26412). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq
melatonin receptor MEL1B,melatonin receptor type 1B