GPER polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast cancer tissue with GPER polyclonal antibody (Cat # PAB26296). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GPER.
Immunogen
A synthetic peptide corresponding to 16 amino acids at 1st cytoplasmic domain of human GPER.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunocytochemistry
Immunohistochemistry
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15-20 ug/mL)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast cancer tissue with GPER polyclonal antibody (Cat # PAB26296). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunocytochemistry
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Gene Info — GPER
Entrez GeneID
2852Protein Accession#
Q99527Gene Name
GPER
Gene Alias
CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678
Gene Description
G protein-coupled estrogen receptor 1
Omim ID
601805Gene Ontology
HyperlinkGene Summary
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq
Other Designations
G protein-coupled receptor 30|IL8-related receptor|OTTHUMP00000115502|chemokine receptor-like 2|constitutively expressed peptide-like receptor|flow-induced endothelial G-protein coupled receptor|heptahelix receptor|leucine rich protein in GPR30 3'UTR
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Interactome
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Disease
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