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EDNRB polyclonal antibody

  • Catalog # : PAB26265
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of EDNRB.
  • Immunogen:
  • A synthetic peptide corresponding to 19 amino acid at C-terminus of human EDNRB.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Dog, Goat, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human blood vessel tissue with EDNRB polyclonal antibody (Cat # PAB26265). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1910
  • Gene Name:
  • EDNRB
  • Gene Alias:
  • ABCDS,ETB,ETBR,ETRB,HSCR,HSCR2
  • Gene Description:
  • endothelin receptor type B
  • Gene Summary:
  • The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000178736,endothelin receptor non-selective type
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