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Last updated: 2016/11/27

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FZD4 polyclonal antibody

  • Catalog # : PAB26258
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of FZD4.
  • Immunogen:
  • A synthetic peptide corresponding to 18 amino acid at N-terminus of human FZD4.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Dog, Hamster, Human, Monkey, Rat
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (30-60 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with FZD4 polyclonal antibody (Cat # PAB26258). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8322
  • Gene Name:
  • FZD4
  • Gene Alias:
  • CD344,EVR1,FEVR,FZD4S,Fz-4,FzE4,GPCR,MGC34390
  • Gene Description:
  • frizzled homolog 4 (Drosophila)
  • Gene Summary:
  • This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq
  • Other Designations:
  • WNT receptor frizzled-4,exudative vitreoretinopathy 1 (autosomal dominant; Criswick-Schepens syndrome),frizzled 4
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