Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human skin (A) and human skeletal muscle tissue (B) with FZD3 polyclonal antibody (Cat # PAB26255). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. [provided by RefSeq