F2RL1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with F2RL1 polyclonal antibody (Cat # PAB26247). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of F2RL1.
Immunogen
A synthetic peptide corresponding to 18 amino acid at extracellular domain of human F2RL1.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NMBR (39%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with F2RL1 polyclonal antibody (Cat # PAB26247). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — F2RL1
Entrez GeneID
2150Protein Accession#
P55085Gene Name
F2RL1
Gene Alias
GPR11, PAR2
Gene Description
coagulation factor II (thrombin) receptor-like 1
Omim ID
600933Gene Ontology
HyperlinkGene Summary
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq
Other Designations
G protein-coupled receptor-11|protease-activated receptor 2|proteinase-activated receptor-2
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Interactome
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Pathway
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Disease
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