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GABBR1 polyclonal antibody

  • Catalog # : PAB26218
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GABBR1.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acid at N-terminus of human GABBR1.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (9-18 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain, Purkinje neurons with GABBR1 polyclonal antibody (Cat # PAB26218). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2550
  • Gene Name:
  • GABBR1
  • Gene Alias:
  • FLJ92613,GABAB(1e),GABABR1,GABBR1-3,GPRC3A,dJ271M21.1.1,dJ271M21.1.2,hGB1a
  • Gene Description:
  • gamma-aminobutyric acid (GABA) B receptor, 1
  • Gene Summary:
  • Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • GABA-B receptor,GABAB, subunit 1c,OTTHUMP00000029114,OTTHUMP00000029115,OTTHUMP00000029116,OTTHUMP00000109099,gamma-aminobutyric acid (GABA) B receptor 1,seven transmembrane helix receptor
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