PNCK polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the PNCK polyclonal antibody (Cat # PAB2621) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PNCK.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PNCK.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the PNCK polyclonal antibody (Cat # PAB2621) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. -
Gene Info — PNCK
Entrez GeneID
139728Protein Accession#
Q6P2M8Gene Name
PNCK
Gene Alias
BSTK3, CaMK1b, FLJ50403, FLJ50549, FLJ56451, FLJ59811, MGC45419
Gene Description
pregnancy up-regulated non-ubiquitously expressed CaM kinase
Omim ID
300680Gene Ontology
HyperlinkGene Summary
PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM
Other Designations
OTTHUMP00000025964|pregnancy upregulated non-ubiquitously expressed CaM kinase
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Publication Reference
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Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.
Deb TB, Coticchia CM, Barndt R, Zuo H, Dickson RB, Johnson MD.
American Journal of Physiology. Cell physiology 2008 Jun; 295(2):C365.
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Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.
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