CYSLTR1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CYSLTR1.
Immunogen
A synthetic peptide corresponding to 20 amino acid at C-terminus of human CYSLTR1.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BRCA1 (45%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (9-22 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human nasal mucosa, allergic rhinitis, eosinophils with CYSLTR1 polyclonal antibody (Cat # PAB26175). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — CYSLTR1
Entrez GeneID
10800Protein Accession#
Q9Y271Gene Name
CYSLTR1
Gene Alias
CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
Gene Description
cysteinyl leukotriene receptor 1
Omim ID
300201Gene Ontology
HyperlinkGene Summary
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq
Other Designations
LTD4 receptor|OTTHUMP00000023596|cysteinyl leukotriene D4 receptor
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