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CYSLTR1 polyclonal antibody

  • Catalog # : PAB26175
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYSLTR1.
  • Immunogen:
  • A synthetic peptide corresponding to 20 amino acid at C-terminus of human CYSLTR1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BRCA1 (45%).
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (9-22 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human nasal mucosa, allergic rhinitis, eosinophils with CYSLTR1 polyclonal antibody (Cat # PAB26175). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • CYSLTR1
  • Gene Alias:
  • CYSLT1,CYSLT1R,CYSLTR,HG55,HMTMF81,MGC46139
  • Gene Description:
  • cysteinyl leukotriene receptor 1
  • Gene Summary:
  • The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq
  • Other Designations:
  • LTD4 receptor,OTTHUMP00000023596,cysteinyl leukotriene D4 receptor
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