BDKRB2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BDKRB2.
Immunogen
A synthetic peptide corresponding to 18 amino acids at C-terminus of human BDKRB2.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BAHD1 (44%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15-30 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain, neurons and glia with BDKRB2 polyclonal antibody (Cat # PAB26164).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunocytochemistry
Immunocytochemical staining of HEK293 human embryonic kidney cells transfected (A) and untransfected (B) with BDKRB2. Primary antibody using BDKRB2 polyclonal antibody (Cat # PAB26164). -
Gene Info — BDKRB2
Entrez GeneID
624Protein Accession#
P30411Gene Name
BDKRB2
Gene Alias
B2R, BK-2, BK2, BKR2, BRB2, DKFZp686O088
Gene Description
bradykinin receptor B2
Omim ID
113503Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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A novel pathogenetic factor of laryngeal attack in hereditary angioedema? Involvement of protease activated receptor 1.
Henriette Farkas, Csilla Máj, István Kenessey, Anna Sebestyén, Ildikó Krencz, Judit Pápay, László Cervenak.
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and C 2022 Jul; 18(1):60.
Application:IHC-P, Human, Human epiglottis.
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A novel pathogenetic factor of laryngeal attack in hereditary angioedema? Involvement of protease activated receptor 1.
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