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CCR8 polyclonal antibody

  • Catalog # : PAB26139
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CCR8.
  • Immunogen:
  • A synthetic peptide corresponding to 19 amino acids at C-terminus of human CCR8.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (22 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human tonsil, germinal center with CCR8 polyclonal antibody (Cat # PAB26139).
    Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1237
  • Gene Name:
  • CCR8
  • Gene Alias:
  • CDw198,CKR-L1,CKRL1,CMKBR8,CMKBRL2,CY6,GPR-CY6,MGC129966,MGC129973,TER1
  • Gene Description:
  • chemokine (C-C motif) receptor 8
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq
  • Other Designations:
  • CC chemokine receptor 8,CC-chemokine receptor chemr1,chemokine (C-C) receptor 8,chemokine (C-C) receptor-like 2
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