BDKRB1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BDKRB1.
Immunogen
A synthetic peptide corresponding to 18 amino acids at extracellular domain of human BDKRB1.
Host
Rabbit
Reactivity
Human, Monkey
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human smooth muscle with BDKRB1 polyclonal antibody (Cat # PAB26133).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — BDKRB1
Entrez GeneID
623Protein Accession#
P46663Gene Name
BDKRB1
Gene Alias
B1BKR, B1R, BKB1R, BKR1, BRADYB1
Gene Description
bradykinin receptor B1
Omim ID
600337Gene Ontology
HyperlinkGene Summary
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq
Other Designations
BK-1 receptor|bradykinin B1 receptor|bradykinin receptor 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
A novel pathogenetic factor of laryngeal attack in hereditary angioedema? Involvement of protease activated receptor 1.
Henriette Farkas, Csilla Máj, István Kenessey, Anna Sebestyén, Ildikó Krencz, Judit Pápay, László Cervenak.
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and C 2022 Jul; 18(1):60.
Application:IHC-P, Human, Human epiglottis.
-
A novel pathogenetic factor of laryngeal attack in hereditary angioedema? Involvement of protease activated receptor 1.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com