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Last updated: 2016/11/27

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CELSR3 polyclonal antibody

  • Catalog # : PAB26116
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CELSR3.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids at N-terminus of human CELSR3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (34 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human brain, Purkinje neurons with CELSR3 polyclonal antibody (Cat # PAB26116).
    Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1951
  • Gene Name:
  • CELSR3
  • Gene Alias:
  • CDHF11,EGFL1,FMI1,HFMI1,MEGF2,RESDA1
  • Gene Description:
  • cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
  • Gene Summary:
  • The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq
  • Other Designations:
  • EGF-like-domain, multiple 1,anchor protein,cadherin EGF LAG seven-pass G-type receptor 3,epidermal growth factor-like 1,multiple EGF-like domains 2
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