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CD97 polyclonal antibody

  • Catalog # : PAB26111
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CD97.
  • Immunogen:
  • A synthetic peptide corresponding to 19 amino acids at N-terminus of human CD97.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MAP3K12 (58%).
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human bone marrow with CD97 polyclonal antibody (Cat # PAB26111).
    Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HEK293 human embryonic kidney cells transfected (A) and untransfected (B) with CD97. Primary antibody using CD97 polyclonal antibody (Cat # PAB26111).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 976
  • Gene Name:
  • CD97
  • Gene Alias:
  • TM7LN1
  • Gene Description:
  • CD97 molecule
  • Gene Summary:
  • This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found. [provided by RefSeq
  • Other Designations:
  • CD97 antigen,leukocyte antigen CD97,seven transmembrane helix receptor,seven-span transmembrane protein,seven-transmembrane, heterodimeric receptor associated with inflammation
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