CXCR5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CXCR5.
Immunogen
A synthetic peptide corresponding to 16 amino acids at cytoplasmic domain of human CXCR5.
Host
Rabbit
Reactivity
Human, Monkey
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTA3 (50%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-18 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen with CXCR5 polyclonal antibody (Cat # PAB26093).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — CXCR5
Entrez GeneID
643Protein Accession#
P32302Gene Name
CXCR5
Gene Alias
BLR1, CD185, MDR15, MGC117347
Gene Description
chemokine (C-X-C motif) receptor 5
Omim ID
601613Gene Ontology
HyperlinkGene Summary
This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. [provided by RefSeq
Other Designations
Burkitt lymphoma receptor 1|Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)|Burkitt lymphoma receptor 1, GTP-binding protein|C-X-C chemokine receptor type 5|monocyte-derived receptor 15
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